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Cross-Reactive Anti-Viral T Cells Increase Prior to an Episode of Viral Reactivation Post Human Lung Transplantation

Human Cytomegalovirus (CMV) reactivation continues to influence lung transplant outcomes. Cross-reactivity of anti-viral memory T cells against donor human leukocyte antigens (HLA) may be a contributing factor. We identified cross-reactive HLA-A*02:01-restricted CMV-specific cytotoxic T lymphocytes...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi H. O., Westall, Glen P., Bull, Tara E., Meehan, Aislin C., Mifsud, Nicole A., Kotsimbos, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566045/
https://www.ncbi.nlm.nih.gov/pubmed/23405250
http://dx.doi.org/10.1371/journal.pone.0056042