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A Multi-Omic Systems-Based Approach Reveals Metabolic Markers of Bacterial Vaginosis and Insight into the Disease

BACKGROUND: Bacterial vaginosis (BV) is the most common vaginal disorder of reproductive-age women. Yet the cause of BV has not been established. To uncover key determinants of BV, we employed a multi-omic, systems-biology approach, including both deep 16S rRNA gene-based sequencing and metabolomics...

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Detalles Bibliográficos
Autores principales: Yeoman, Carl J., Thomas, Susan M., Miller, Margret E. Berg, Ulanov, Alexander V., Torralba, Manolito, Lucas, Sarah, Gillis, Marcus, Cregger, Melissa, Gomez, Andres, Ho, Mengfei, Leigh, Steven R., Stumpf, Rebecca, Creedon, Douglas J., Smith, Michael A., Weisbaum, Jon S., Nelson, Karen E., Wilson, Brenda A., White, Bryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566083/
https://www.ncbi.nlm.nih.gov/pubmed/23405259
http://dx.doi.org/10.1371/journal.pone.0056111