β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion via Rap1 and IQGAP1

β-arrestins play critical roles in chemotaxis and cytoskeletal reorganization downstream of several receptor types, including G protein-coupled receptors (GPCRs), which are targets for greater than 50% of all pharmaceuticals. Among them, receptors for lysophosphatidic acid (LPA), namely LPA(1) are o...

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Detalles Bibliográficos
Autores principales: Alemayehu, Mistre, Dragan, Magdalena, Pape, Cynthia, Siddiqui, Iram, Sacks, David B., Di Guglielmo, Gianni M., Babwah, Andy V., Bhattacharya, Moshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566084/
https://www.ncbi.nlm.nih.gov/pubmed/23405264
http://dx.doi.org/10.1371/journal.pone.0056174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566084/
https://www.ncbi.nlm.nih.gov/pubmed/23405264
http://dx.doi.org/10.1371/journal.pone.0056174

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