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Activation of WIP1 Phosphatase by HTLV-1 Tax Mitigates the Cellular Response to DNA Damage

Genomic instability stemming from dysregulation of cell cycle checkpoints and DNA damage response (DDR) is a common feature of many cancers. The cancer adult T cell leukemia (ATL) can occur in individuals infected with human T cell leukemia virus type 1 (HTLV-1), and ATL cells contain extensive chro...

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Detalles Bibliográficos
Autores principales: Dayaram, Tajhal, Lemoine, Francene J., Donehower, Lawrence A., Marriott, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566092/
https://www.ncbi.nlm.nih.gov/pubmed/23405243
http://dx.doi.org/10.1371/journal.pone.0055989