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Microsatellite Tandem Repeats Are Abundant in Human Promoters and Are Associated with Regulatory Elements

Tandem repeats are genomic elements that are prone to changes in repeat number and are thus often polymorphic. These sequences are found at a high density at the start of human genes, in the gene’s promoter. Increasing empirical evidence suggests that length variation in these tandem repeats can aff...

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Detalles Bibliográficos
Autores principales: Sawaya, Sterling, Bagshaw, Andrew, Buschiazzo, Emmanuel, Kumar, Pankaj, Chowdhury, Shantanu, Black, Michael A., Gemmell, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566118/
https://www.ncbi.nlm.nih.gov/pubmed/23405090
http://dx.doi.org/10.1371/journal.pone.0054710