CYLD Regulates RhoA Activity by Modulating LARG Ubiquitination

Rho family guanosine triphosphatases (GTPases), such as RhoA, Cdc42, and Rac1, play a fundamental role in various cellular processes. The activation of Rho proteins is catalyzed by guanine nucleotide-exchange factors (GEFs), which promote the exchange of GDP for GTP. The precise mechanisms regulatin...

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Detalles Bibliográficos
Autores principales: Yang, Yunfan, Sun, Lei, Tala, Gao, Jinmin, Li, Dengwen, Zhou, Jun, Liu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566121/
https://www.ncbi.nlm.nih.gov/pubmed/23405219
http://dx.doi.org/10.1371/journal.pone.0055833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566121/
https://www.ncbi.nlm.nih.gov/pubmed/23405219
http://dx.doi.org/10.1371/journal.pone.0055833

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