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Chronic Delivery of a Thrombospondin-1 Mimetic Decreases Skeletal Muscle Capillarity in Mice

Angiogenesis is an essential process for normal skeletal muscle function. There is a growing body of evidence suggesting that thrombospondin-1 (TSP-1), a potent antiangiogenic protein in tumorigenesis, is an important regulator of both physiological and pathological skeletal muscle angiogenesis. We...

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Detalles Bibliográficos
Autores principales: Audet, Gerald N., Fulks, Daniel, Stricker, Janelle C., Olfert, I. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566122/
https://www.ncbi.nlm.nih.gov/pubmed/23405239
http://dx.doi.org/10.1371/journal.pone.0055953