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Differential Phosphorylation of Perilipin 1A at the Initiation of Lipolysis Revealed by Novel Monoclonal Antibodies and High Content Analysis

Lipolysis in adipocytes is regulated by phosphorylation of lipid droplet-associated proteins, including perilipin 1A and hormone-sensitive lipase (HSL). Perilipin 1A is potentially phosphorylated by cAMP(adenosine 3′,5′-cyclic monophosphate)-dependent protein kinase (PKA) on several sites, including...

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Detalles Bibliográficos
Autores principales: McDonough, Patrick M., Maciejewski-Lenoir, Dominique, Hartig, Sean M., Hanna, Rita A., Whittaker, Ross, Heisel, Andrew, Nicoll, James B., Buehrer, Benjamin M., Christensen, Kurt, Mancini, Maureen G., Mancini, Michael A., Edwards, Dean P., Price, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566132/
https://www.ncbi.nlm.nih.gov/pubmed/23405163
http://dx.doi.org/10.1371/journal.pone.0055511