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Differential Phosphorylation of Perilipin 1A at the Initiation of Lipolysis Revealed by Novel Monoclonal Antibodies and High Content Analysis
Lipolysis in adipocytes is regulated by phosphorylation of lipid droplet-associated proteins, including perilipin 1A and hormone-sensitive lipase (HSL). Perilipin 1A is potentially phosphorylated by cAMP(adenosine 3′,5′-cyclic monophosphate)-dependent protein kinase (PKA) on several sites, including...
Autores principales: | McDonough, Patrick M., Maciejewski-Lenoir, Dominique, Hartig, Sean M., Hanna, Rita A., Whittaker, Ross, Heisel, Andrew, Nicoll, James B., Buehrer, Benjamin M., Christensen, Kurt, Mancini, Maureen G., Mancini, Michael A., Edwards, Dean P., Price, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566132/ https://www.ncbi.nlm.nih.gov/pubmed/23405163 http://dx.doi.org/10.1371/journal.pone.0055511 |
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