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Molecular Analysis of the Prostacyclin Receptor’s Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1

The prostanoid prostacyclin, or prostaglandin I(2), plays an essential role in many aspects of cardiovascular disease. The actions of prostacyclin are mainly mediated through its activation of the prostacyclin receptor or, in short, the IP. In recent studies, the cytoplasmic carboxy-terminal domain...

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Detalles Bibliográficos
Autores principales: Birrane, Gabriel, Mulvaney, Eamon P., Pal, Rinku, Kinsella, B. Therese, Kocher, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566133/
https://www.ncbi.nlm.nih.gov/pubmed/23457445
http://dx.doi.org/10.1371/journal.pone.0053819