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Vitamin D(3) at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

BACKGROUND: We previously demonstrated that dietary vitamin D(3) at 10x the adequate intake (AI) attenuates the decline in functional capacity in the G93A mouse model of ALS. We hypothesized that higher doses would elicit more robust changes in functional and disease outcomes. OBJECTIVE: To determin...

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Detalles Bibliográficos
Autores principales: Gianforcaro, Alexandro, Solomon, Jesse A., Hamadeh, Mazen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566148/
https://www.ncbi.nlm.nih.gov/pubmed/23405058
http://dx.doi.org/10.1371/journal.pone.0030243