Tricyclic Benzo[cd]azulenes Selectively Inhibit Activities of Pim Kinases and Restrict Growth of Epstein-Barr Virus-Transformed Cells

Oncogenic Pim family kinases are often overexpressed in human hematopoietic malignancies as well as in solid tumours. These kinases contribute to tumorigenesis by promoting cell survival and by enhancing resistance against chemotherapy and radiation therapy. Furthermore, we have recently shown that...

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Detalles Bibliográficos
Autores principales: Kiriazis, Alexandros, Vahakoski, Riitta L., Santio, Niina M., Arnaudova, Ralica, Eerola, Sini K., Rainio, Eeva-Marja, Aumüller, Ingo B., Yli-Kauhaluoma, Jari, Koskinen, Päivi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566155/
https://www.ncbi.nlm.nih.gov/pubmed/23405147
http://dx.doi.org/10.1371/journal.pone.0055409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566155/
https://www.ncbi.nlm.nih.gov/pubmed/23405147
http://dx.doi.org/10.1371/journal.pone.0055409

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