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A Critical Role for MAPK Signalling Pathways in the Transcriptional Regulation of Toll Like Receptors
Toll-like Receptors (TLR) are phylogenetically conserved transmembrane proteins responsible for detection of pathogens and activation of immune responses in diverse animal species. The stimulation of TLR by pathogen-derived molecules leads to the production of pro-inflammatory mediators including cy...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566169/ https://www.ncbi.nlm.nih.gov/pubmed/23405061 http://dx.doi.org/10.1371/journal.pone.0051243 |