Horizontal Transmission of Malignancy: In-Vivo Fusion of Human Lymphomas with Hamster Stroma Produces Tumors Retaining Human Genes and Lymphoid Pathology

We report the in-vivo fusion of two Hodgkin lymphomas with golden hamster cheek pouch cells, resulting in serially-transplanted (over 5–6 years) GW-532 and GW-584 heterosynkaryon tumor cells displaying both human and hamster DNA (by FISH), lymphoma-like morphology, aggressive metastasis, and retenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Goldenberg, David M., Gold, David V., Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing, Jaffe, Elaine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566191/
https://www.ncbi.nlm.nih.gov/pubmed/23405135
http://dx.doi.org/10.1371/journal.pone.0055324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566191/
https://www.ncbi.nlm.nih.gov/pubmed/23405135
http://dx.doi.org/10.1371/journal.pone.0055324

Ejemplares similares