The Two-Component Adjuvant IC31® Boosts Type I Interferon Production of Human Monocyte-Derived Dendritic Cells via Ligation of Endosomal TLRs

The aim of this study was to characterize and identify the mode of action of IC31®, a two-component vaccine adjuvant. We found that IC31® was accumulated in human peripheral blood monocytes, MHC class II positive cells and monocyte-derived DCs (moDCs) but not in plasmacytoid DCs (pDCs). In the prese...

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Detalles Bibliográficos
Autores principales: Szabo, Attila, Gogolak, Peter, Pazmandi, Kitti, Kis-Toth, Katalin, Riedl, Karin, Wizel, Benjamin, Lingnau, Karen, Bacsi, Attila, Rethi, Bence, Rajnavolgyi, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566214/
https://www.ncbi.nlm.nih.gov/pubmed/23405128
http://dx.doi.org/10.1371/journal.pone.0055264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566214/
https://www.ncbi.nlm.nih.gov/pubmed/23405128
http://dx.doi.org/10.1371/journal.pone.0055264

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