Suppression of Jab1/CSN5 induces radiation- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated malignancy most common in East Asia and Africa. Radiotherapy and cisplatin-based chemotherapy are the main treatment options. Unfortunately, disease response to concurrent chemoradiotherapy varies among patients with NPC, and many ca...

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Detalles Bibliográficos
Autores principales: Pan, Yunbao, Zhang, Qingxiu, Atsaves, Vasileios, Yang, Huiling, Claret, Francois X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566273/
https://www.ncbi.nlm.nih.gov/pubmed/22797071
http://dx.doi.org/10.1038/onc.2012.294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566273/
https://www.ncbi.nlm.nih.gov/pubmed/22797071
http://dx.doi.org/10.1038/onc.2012.294

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