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Suppression of Jab1/CSN5 induces radiation- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated malignancy most common in East Asia and Africa. Radiotherapy and cisplatin-based chemotherapy are the main treatment options. Unfortunately, disease response to concurrent chemoradiotherapy varies among patients with NPC, and many ca...
Autores principales: | Pan, Yunbao, Zhang, Qingxiu, Atsaves, Vasileios, Yang, Huiling, Claret, Francois X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566273/ https://www.ncbi.nlm.nih.gov/pubmed/22797071 http://dx.doi.org/10.1038/onc.2012.294 |
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