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Phosphorylation at Ser(26) in the ATP-binding site of Ca(2+)/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity

CaMKII (Ca(2+)/calmodulin-dependent kinase II) is a serine/threonine phosphotransferase that is capable of long-term retention of activity due to autophosphorylation at a specific threonine residue within each subunit of its oligomeric structure. The γ isoform of CaMKII is a significant regulator of...

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Detalles Bibliográficos
Autores principales: Yilmaz, Mehtap, Gangopadhyay, Samudra S., Leavis, Paul, Grabarek, Zenon, Morgan, Kathleen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566533/
https://www.ncbi.nlm.nih.gov/pubmed/23289753
http://dx.doi.org/10.1042/BSR20120116