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Phosphorylation at Ser(26) in the ATP-binding site of Ca(2+)/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity
CaMKII (Ca(2+)/calmodulin-dependent kinase II) is a serine/threonine phosphotransferase that is capable of long-term retention of activity due to autophosphorylation at a specific threonine residue within each subunit of its oligomeric structure. The γ isoform of CaMKII is a significant regulator of...
Autores principales: | Yilmaz, Mehtap, Gangopadhyay, Samudra S., Leavis, Paul, Grabarek, Zenon, Morgan, Kathleen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566533/ https://www.ncbi.nlm.nih.gov/pubmed/23289753 http://dx.doi.org/10.1042/BSR20120116 |
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