Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A

Previously we have shown that intradermal (i.d.) immunization with a recombinant adenovirus expressing antigen 85A (Ad85A) induced a strong splenic CD8 T cell response in BALB/c mice but a weak lung immune response and did not protect mice against challenge with Mycobacterium tuberculosis (Mtb). Aft...

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Detalles Bibliográficos
Autores principales: Beverley, Peter, Ronan, Edward, Lee, Lianni, Arnold, Isabelle, Bolinger, Beatrice, Powrie, Fiona, Tchilian, Elma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566543/
https://www.ncbi.nlm.nih.gov/pubmed/23262169
http://dx.doi.org/10.1016/j.vaccine.2012.12.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566543/
https://www.ncbi.nlm.nih.gov/pubmed/23262169
http://dx.doi.org/10.1016/j.vaccine.2012.12.024

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