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Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest

Catechol-O-methyltransferase (COMT) modulates dopamine in the prefrontal cortex (PFC) and influences PFC dopamine-dependent cognitive task performance. A human COMT polymorphism (Val(158)Met) alters enzyme activity and is associated with both the activation and functional connectivity of the PFC dur...

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Detalles Bibliográficos
Autores principales: Tunbridge, Elizabeth M., Farrell, Sarah M., Harrison, Paul J., Mackay, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566589/
https://www.ncbi.nlm.nih.gov/pubmed/23228511
http://dx.doi.org/10.1016/j.neuroimage.2012.11.059