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Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest
Catechol-O-methyltransferase (COMT) modulates dopamine in the prefrontal cortex (PFC) and influences PFC dopamine-dependent cognitive task performance. A human COMT polymorphism (Val(158)Met) alters enzyme activity and is associated with both the activation and functional connectivity of the PFC dur...
Autores principales: | Tunbridge, Elizabeth M., Farrell, Sarah M., Harrison, Paul J., Mackay, Clare E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566589/ https://www.ncbi.nlm.nih.gov/pubmed/23228511 http://dx.doi.org/10.1016/j.neuroimage.2012.11.059 |
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