Interconverting Conformations of Slipped-DNA Junctions Formed by Trinucleotide Repeats Affect Repair Outcome

[Image: see text] Expansions of (CTG)·(CAG) repeated DNAs are the mutagenic cause of 14 neurological diseases, likely arising through the formation and processing of slipped-strand DNAs. These transient intermediates of repeat length mutations are formed by out-of-register mispairing of repeat units...

Descripción completa

Detalles Bibliográficos
Autores principales: Slean, Meghan M., Reddy, Kaalak, Wu, Bin, Nichol Edamura, Kerrie, Kekis, Mariana, Nelissen, Frank H. T., Aspers, Ruud L. E. G., Tessari, Marco, Schärer, Orlando D., Wijmenga, Sybren S., Pearson, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566650/
https://www.ncbi.nlm.nih.gov/pubmed/23339280
http://dx.doi.org/10.1021/bi301369b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566650/
https://www.ncbi.nlm.nih.gov/pubmed/23339280
http://dx.doi.org/10.1021/bi301369b

Ejemplares similares