Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene–gene–environment interaction

Epistatic gene–gene interactions could contribute to the heritability of complex multigenic disorders, but few examples have been reported. Here, we focus on the role of aberrant dopaminergic signaling, involving the dopamine transporter DAT, a cocaine target, and the dopamine D2 receptor, which phy...

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Detalles Bibliográficos
Autores principales: Sullivan, D, Pinsonneault, J K, Papp, A C, Zhu, H, Lemeshow, S, Mash, D C, Sadee, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566726/
https://www.ncbi.nlm.nih.gov/pubmed/23340505
http://dx.doi.org/10.1038/tp.2012.146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566726/
https://www.ncbi.nlm.nih.gov/pubmed/23340505
http://dx.doi.org/10.1038/tp.2012.146

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