1–42 β-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

1–42 β-Amyloid (Aβ(1–42)) peptide is a key molecule involved in the development of Alzheimer's disease. Some of its effects are manifested at the neuronal morphological level. These morphological changes involve loss of neurites due to cytoskeleton alterations. However, the mechanism of Aβ(1–42...

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Detalles Bibliográficos
Autores principales: Manterola, L, Hernando-Rodríguez, M, Ruiz, A, Apraiz, A, Arrizabalaga, O, Vellón, L, Alberdi, E, Cavaliere, F, Lacerda, H M, Jimenez, S, Parada, L A, Matute, C, Zugaza, J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566727/
https://www.ncbi.nlm.nih.gov/pubmed/23340502
http://dx.doi.org/10.1038/tp.2012.147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566727/
https://www.ncbi.nlm.nih.gov/pubmed/23340502
http://dx.doi.org/10.1038/tp.2012.147

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