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Development of peptidomimetic ligands of Pro-Leu-Gly-NH(2) as allosteric modulators of the dopamine D(2) receptor

A variety of stable, small-molecule peptidomimetic ligands have been developed to elucidate the mechanism by which the neuropeptide Pro-Leu-Gly-NH(2) (PLG) modulates dopaminergic neurotransmission. Photoaffinity labeling ligands based upon PLG peptidomimetics have been used to establish that PLG bin...

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Detalles Bibliográficos
Autores principales: Bhagwanth, Swapna, Mishra, Ram K, Johnson, Rodney L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566759/
https://www.ncbi.nlm.nih.gov/pubmed/23400263
http://dx.doi.org/10.3762/bjoc.9.24