Cargando…

Targeted and genome-scale methylomics reveals gene body signatures in human cell lines

Cytosine methylation, an epigenetic modification of DNA, is a target of growing interest for developing high throughput profiling technologies. Here we introduce two new, complementary techniques for cytosine methylation profiling utilizing next generation sequencing technology: bisulfite padlock pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ball, Madeleine Price, Li, Jin Billy, Gao, Yuan, Lee, Je-Hyuk, LeProust, Emily, Park, In-Hyun, Xie, Bin, Daley, George Q., Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566772/
https://www.ncbi.nlm.nih.gov/pubmed/19329998
http://dx.doi.org/10.1038/nbt.1533