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Targeted and genome-scale methylomics reveals gene body signatures in human cell lines
Cytosine methylation, an epigenetic modification of DNA, is a target of growing interest for developing high throughput profiling technologies. Here we introduce two new, complementary techniques for cytosine methylation profiling utilizing next generation sequencing technology: bisulfite padlock pr...
Autores principales: | Ball, Madeleine Price, Li, Jin Billy, Gao, Yuan, Lee, Je-Hyuk, LeProust, Emily, Park, In-Hyun, Xie, Bin, Daley, George Q., Church, George M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566772/ https://www.ncbi.nlm.nih.gov/pubmed/19329998 http://dx.doi.org/10.1038/nbt.1533 |
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