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Synthesis of 5-(ethylsulfonyl)-2-methoxyaniline: An important pharmacological fragment of VEGFR2 and other inhibitors

Background: 5-(Ethylsulfonyl)-2-methoxyaniline (5) is part of the structure in 131 compounds possessing different biological activities. In most cases, they have antitumor properties (112 compounds). Other compounds are described as cardiovascular agents, ion-channel blockers, nervous-system blocker...

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Detalles Bibliográficos
Autores principales: Murár, Miroslav, Addová, Gabriela, Boháč, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566798/
https://www.ncbi.nlm.nih.gov/pubmed/23399884
http://dx.doi.org/10.3762/bjoc.9.20