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Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells
BACKGROUND: Melatonin induces apoptosis in many different cancer cell lines, including hepatocellular carcinoma cells. However, the responsible pathways have not been clearly elucidated. A member of the forkhead transcription factors' family, FoxO3a, has been implicated in the expression of the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566813/ https://www.ncbi.nlm.nih.gov/pubmed/23257900 http://dx.doi.org/10.1038/bjc.2012.563 |