High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates

BACKGROUND: The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consists of cells filled – almost exclusively – with aberrant mitochondria. In turn,...

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Detalles Bibliográficos
Autores principales: Karbownik-Lewińska, Małgorzata, Stępniak, Jan, Lewiński, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566933/
https://www.ncbi.nlm.nih.gov/pubmed/23267669
http://dx.doi.org/10.1186/1756-6614-5-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566933/
https://www.ncbi.nlm.nih.gov/pubmed/23267669
http://dx.doi.org/10.1186/1756-6614-5-24

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