Cargando…
High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates
BACKGROUND: The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consists of cells filled – almost exclusively – with aberrant mitochondria. In turn,...
Autores principales: | Karbownik-Lewińska, Małgorzata, Stępniak, Jan, Lewiński, Andrzej |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566933/ https://www.ncbi.nlm.nih.gov/pubmed/23267669 http://dx.doi.org/10.1186/1756-6614-5-24 |
Ejemplares similares
-
Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates
por: Stępniak, Jan, et al.
Publicado: (2022) -
Fenton Reaction-Induced Oxidative Damage to Membrane Lipids and Protective Effects of 17β-Estradiol in Porcine Ovary and Thyroid Homogenates
por: Rynkowska, Aleksandra, et al.
Publicado: (2020) -
Potassium iodide, but not potassium iodate, as a potential protective agent against oxidative damage to membrane lipids in porcine thyroid
por: Milczarek, Magdalena, et al.
Publicado: (2013) -
Protective effect of KI in mtDNA in porcine thyroid: comparison with KIO(3) and nDNA
por: Karbownik-Lewinska, Malgorzata, et al.
Publicado: (2014) -
Sorafenib versus Lenvatinib Causes Stronger Oxidative Damage to Membrane Lipids in Noncancerous Tissues of the Thyroid, Liver, and Kidney: Effective Protection by Melatonin and Indole-3-Propionic Acid
por: Stępniak, Jan, et al.
Publicado: (2022)