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Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin

BACKGROUND: Colon cancer stem cells may drive carcinogenesis and account for chemotherapeutic failure. Although many markers for these cells have been proposed, there is no complete agreement regarding them, nor has their presence in the early phases of carcinogenesis been characterized in depth. ME...

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Detalles Bibliográficos
Autores principales: Femia, Angelo Pietro, Dolara, Piero, Salvadori, Maddalena, Caderni, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566940/
https://www.ncbi.nlm.nih.gov/pubmed/23374535
http://dx.doi.org/10.1186/1471-2407-13-48