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Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway

BACKGROUND: Chronic periodontitis is an infectious disease of the periodontium, which includes the gingival epithelium, periodontal ligament and alveolar bone. The signature clinical feature of periodontitis is resorption of alveolar bone and subsequent tooth loss. The Gram-negative oral anaerobe, P...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjian, Ju, Jun, Rigney, Todd, Tribble, Gena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566952/
https://www.ncbi.nlm.nih.gov/pubmed/23305098
http://dx.doi.org/10.1186/1471-2180-13-5