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Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway
BACKGROUND: Chronic periodontitis is an infectious disease of the periodontium, which includes the gingival epithelium, periodontal ligament and alveolar bone. The signature clinical feature of periodontitis is resorption of alveolar bone and subsequent tooth loss. The Gram-negative oral anaerobe, P...
Autores principales: | Zhang, Wenjian, Ju, Jun, Rigney, Todd, Tribble, Gena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566952/ https://www.ncbi.nlm.nih.gov/pubmed/23305098 http://dx.doi.org/10.1186/1471-2180-13-5 |
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