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Leukocyte DNA as Surrogate for the Evaluation of Imprinted Loci Methylation in Mammary Tissue DNA

There is growing interest in identifying surrogate tissues to identify epimutations in cancer patients since primary target tissues are often difficult to obtain. Methylation patterns at imprinted loci are established during gametogenesis and post fertilization and their alterations have been associ...

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Detalles Bibliográficos
Autores principales: Barault, Ludovic, Ellsworth, Rachel E., Harris, Holly R., Valente, Allyson L., Shriver, Craig D., Michels, Karin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567003/
https://www.ncbi.nlm.nih.gov/pubmed/23409079
http://dx.doi.org/10.1371/journal.pone.0055896