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Dramatic Structural Changes Resulting from the Loss of a Crucial Hydrogen Bond in the Hinge Region Involved in C-Terminal Helix Swapping in SurE: A Survival Protein from Salmonella typhimurium

Domain swapping is an interesting feature of some oligomeric proteins in which each protomer of the oligomer provides an identical surface for exclusive interaction with a segment or domain belonging to another protomer. Here we report results of mutagenesis experiments on the structure of C-termina...

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Detalles Bibliográficos
Autores principales: Mathiharan, Yamuna Kalyani, Pappachan, Anju, Savithri, H. S., Murthy, Mathur R. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567009/
https://www.ncbi.nlm.nih.gov/pubmed/23409101
http://dx.doi.org/10.1371/journal.pone.0055978