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The N-Terminal Region of Nurr1 (a.a 1–31) Is Essential for Its Efficient Degradation by the Ubiquitin Proteasome Pathway

NURR1/NR4A2 is an orphan nuclear receptor that is critical for the development and maintenance of mesencephalic dopaminergic neurons and regulates transcription of genes involved in the function of dopaminergic neurons directly via specific NGFI-B response elements (NBRE).and substantial data suppor...

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Detalles Bibliográficos
Autores principales: Alvarez-Castelao, Beatriz, Losada, Fernando, Ahicart, Patrícia, Castaño, Jose G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567022/
https://www.ncbi.nlm.nih.gov/pubmed/23409108
http://dx.doi.org/10.1371/journal.pone.0055999