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Massive-Scale Gene Co-Expression Network Construction and Robustness Testing Using Random Matrix Theory

The study of gene relationships and their effect on biological function and phenotype is a focal point in systems biology. Gene co-expression networks built using microarray expression profiles are one technique for discovering and interpreting gene relationships. A knowledge-independent thresholdin...

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Detalles Bibliográficos
Autores principales: Gibson, Scott M., Ficklin, Stephen P., Isaacson, Sven, Luo, Feng, Feltus, Frank A., Smith, Melissa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567026/
https://www.ncbi.nlm.nih.gov/pubmed/23409071
http://dx.doi.org/10.1371/journal.pone.0055871