Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian Carcinoma

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from Italian OC patients...

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Detalles Bibliográficos
Autores principales: De Marco, Carmela, Rinaldo, Nicola, Bruni, Paola, Malzoni, Carmine, Zullo, Fulvio, Fabiani, Fernanda, Losito, Simona, Scrima, Marianna, Marino, Federica Zito, Franco, Renato, Quintiero, Alfina, Agosti, Valter, Viglietto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567053/
https://www.ncbi.nlm.nih.gov/pubmed/23408974
http://dx.doi.org/10.1371/journal.pone.0055362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567053/
https://www.ncbi.nlm.nih.gov/pubmed/23408974
http://dx.doi.org/10.1371/journal.pone.0055362

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