Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral Reflux

PURPOSE: Pax3cre-mediated deletion of fibroblast growth factor receptor 2 (Fgfr2) broadly in renal and urinary tract mesenchyme led to ureteric bud (UB) induction defects and vesicoureteral reflux (VUR), although the mechanisms were unclear. Here, we investigated whether Fgfr2 acts specifically in p...

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Detalles Bibliográficos
Autores principales: Walker, Kenneth A., Sims-Lucas, Sunder, Di Giovanni, Valeria E., Schaefer, Caitlin, Sunseri, Whitney M., Novitskaya, Tatiana, de Caestecker, Mark P., Chen, Feng, Bates, Carlton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567073/
https://www.ncbi.nlm.nih.gov/pubmed/23409123
http://dx.doi.org/10.1371/journal.pone.0056062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567073/
https://www.ncbi.nlm.nih.gov/pubmed/23409123
http://dx.doi.org/10.1371/journal.pone.0056062

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