Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea

BACKGROUND: Fetal hemoglobin level is a heritable complex trait that strongly correlates swith the clinical severity of sickle cell disease. Only few genetic loci have been identified as robustly associated with fetal hemoglobin in patients with sickle cell disease, primarily adults. The sole approv...

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Detalles Bibliográficos
Autores principales: Green, Nancy S., Ender, Katherine L., Pashankar, Farzana, Driscoll, Catherine, Giardina, Patricia J., Mullen, Craig A., Clark, Lorraine N., Manwani, Deepa, Crotty, Jennifer, Kisselev, Sergey, Neville, Kathleen A., Hoppe, Carolyn, Barral, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567082/
https://www.ncbi.nlm.nih.gov/pubmed/23409025
http://dx.doi.org/10.1371/journal.pone.0055709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567082/
https://www.ncbi.nlm.nih.gov/pubmed/23409025
http://dx.doi.org/10.1371/journal.pone.0055709

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