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eIF4GI Facilitates the MicroRNA-Mediated Gene Silencing

MicroRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional gene silencing by binding to complementary target mRNAs and recruiting the miRNA-containing ribonucleoprotein complexes to the mRNAs. However, the molecular basis of this silencing is unclear. Here, we show that human Ago2...

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Detalles Bibliográficos
Autores principales: Ryu, Incheol, Park, Ji Hoon, An, Sihyeon, Kwon, Oh Sung, Jang, Sung Key
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567085/
https://www.ncbi.nlm.nih.gov/pubmed/23409027
http://dx.doi.org/10.1371/journal.pone.0055725