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Estrogen Induction of Telomerase Activity through Regulation of the Mitogen-Activated Protein Kinase (MAPK) Dependent Pathway in Human Endometrial Cancer Cells

Given that prolonged exposure to estrogen and increased telomerase activity are associated with endometrial carcinogenesis, our objective was to evaluate the interaction between the MAPK pathway and estrogen induction of telomerase activity in endometrial cancer cells. Estradiol (E2) induced telomer...

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Detalles Bibliográficos
Autores principales: Zhou, Chunxiao, Steplowski, Tara A., Dickens, Hallum K., Malloy, Kimberly M., Gehrig, Paola A., Boggess, John F., Bae-Jump, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567109/
https://www.ncbi.nlm.nih.gov/pubmed/23409030
http://dx.doi.org/10.1371/journal.pone.0055730