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Integrin-Mediated Signaling Induced by Simian Virus 40 Leads to Transient Uncoupling of Cortical Actin and the Plasma Membrane

Simian Virus 40 (SV40) is a paradigm pathogen with multivalent binding sites for the sphingolipid GM1, via which it induces its endocytosis for infection. Here we report that SV40 also utilizes cell surface integrins to activate signaling networks required for infection, even in the absence of the p...

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Detalles Bibliográficos
Autores principales: Stergiou, Lilli, Bauer, Manuel, Mair, Waltraud, Bausch-Fluck, Damaris, Drayman, Nir, Wollscheid, Bernd, Oppenheim, Ariella, Pelkmans, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567119/
https://www.ncbi.nlm.nih.gov/pubmed/23409046
http://dx.doi.org/10.1371/journal.pone.0055799