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Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling

Cellular signal transduction generally involves cascades of post-translational protein modifications that rapidly catalyze changes in protein-DNA interactions and gene expression. High-throughput measurements are improving our ability to study each of these stages individually, but do not capture th...

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Detalles Bibliográficos
Autores principales: Huang, Shao-shan Carol, Clarke, David C., Gosline, Sara J. C., Labadorf, Adam, Chouinard, Candace R., Gordon, William, Lauffenburger, Douglas A., Fraenkel, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567149/
https://www.ncbi.nlm.nih.gov/pubmed/23408876
http://dx.doi.org/10.1371/journal.pcbi.1002887