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Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling
Cellular signal transduction generally involves cascades of post-translational protein modifications that rapidly catalyze changes in protein-DNA interactions and gene expression. High-throughput measurements are improving our ability to study each of these stages individually, but do not capture th...
Autores principales: | Huang, Shao-shan Carol, Clarke, David C., Gosline, Sara J. C., Labadorf, Adam, Chouinard, Candace R., Gordon, William, Lauffenburger, Douglas A., Fraenkel, Ernest |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567149/ https://www.ncbi.nlm.nih.gov/pubmed/23408876 http://dx.doi.org/10.1371/journal.pcbi.1002887 |
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