Cargando…

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes

The actions of the RIG-I like receptor (RLR) and type I interferon (IFN) signaling pathways are essential for a protective innate immune response against the emerging flavivirus West Nile virus (WNV). In mice lacking RLR or IFN signaling pathways, WNV exhibits enhanced tissue tropism, indicating tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suthar, Mehul S., Brassil, Margaret M., Blahnik, Gabriele, McMillan, Aimee, Ramos, Hilario J., Proll, Sean C., Belisle, Sarah E., Katze, Michael G., Gale, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567171/ https://www.ncbi.nlm.nih.gov/pubmed/23544010 http://dx.doi.org/10.1371/journal.ppat.1003168

Ejemplares similares

IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection
por: Ramos, Hilario J., et al.
Publicado: (2012)

The Innate Immune Playbook for Restricting West Nile Virus Infection
por: Quicke, Kendra M., et al.
Publicado: (2013)

Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes
por: Graham, Jessica B., et al.
Publicado: (2015)

Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8(+) T Cell Immune Responses against West Nile Virus Infection
por: Brien, James D., et al.
Publicado: (2011)

Systems analysis of West Nile virus infection
por: Suthar, Mehul S, et al.
Publicado: (2014)

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
por: Suthar, Mehul S., et al.
Publicado: (2010)

Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses
por: Roe, Kelsey, et al.
Publicado: (2019)

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7
por: Daffis, Stephane, et al.
Publicado: (2009)

Splenic macrophages are required for protective innate immunity against West Nile virus
por: Bryan, Marianne A., et al.
Publicado: (2018)

Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
por: Cho, Hyelim, et al.
Publicado: (2013)

Pathology and tissue tropism of natural West Nile virus infection in birds: a review
por: Gamino, Virginia, et al.
Publicado: (2013)

The Role of Innate Immunity in Conditioning Mosquito Susceptibility to West Nile Virus
por: Prasad, Abhishek N., et al.
Publicado: (2013)

A Mouse Model of Chronic West Nile Virus Disease
por: Graham, Jessica B., et al.
Publicado: (2016)

Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response
por: Walters, Kathie-Anne, et al.
Publicado: (2006)

Innate Immune Sensing of Flaviviruses
por: Suthar, Mehul S., et al.
Publicado: (2013)

Antiviral Cytokine Response in Neuroinvasive and Non-Neuroinvasive West Nile Virus Infection
por: Zidovec-Lepej, Snjezana, et al.
Publicado: (2021)

Insulin-mediated endothelin signaling is antiviral during West Nile virus infection
por: Trammell, Chasity E., et al.
Publicado: (2023)

Management of West Nile Encephalitis: An Uncommon Complication of West Nile Virus
por: Alli, Ammar, et al.
Publicado: (2021)

Mechanisms of innate immune evasion in re-emerging RNA viruses
por: Ma, Daphne Y, et al.
Publicado: (2015)

Protective Behavior and West Nile Virus Risk
por: Loeb, Mark, et al.
Publicado: (2005)

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
por: Ramos, Hilario J, et al.
Publicado: (2011)

Systems biology: A tool for charting the antiviral landscape
por: Bowen, James R., et al.
Publicado: (2016)

West Nile Virus in Farmed Alligators
por: Miller, Debra L., et al.
Publicado: (2003)

Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross
por: Green, Richard, et al.
Publicado: (2017)

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques
por: O’Connor, Megan A., et al.
Publicado: (2018)

In vitro and in vivo characterization of a West Nile virus MAD78 infectious clone
por: Hussmann, Katherine L., et al.
Publicado: (2014)

Alligators as West Nile Virus Amplifiers
por: Klenk, Kaci, et al.
Publicado: (2004)

Emerging complexity and new roles for the RIG-I-like receptors in innate antiviral immunity
por: Errett, John S., et al.
Publicado: (2015)

ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitro
por: Dai, Jianfeng, et al.
Publicado: (2011)

Evaluation of West Nile Virus Education Campaign
por: Averett, Ellen, et al.
Publicado: (2005)

West Nile Virus, Venezuela
por: Bosch, Irene, et al.
Publicado: (2007)

West Nile Virus in California
por: Reisen, William, et al.
Publicado: (2004)

West Nile Virus, Guadeloupe
por: Quirin, René, et al.
Publicado: (2004)

West Nile fever in Czechland.
por: Hubálek, Z, et al.
Publicado: (1999)

West Nile Virus in Slovenia
por: Knap, Nataša, et al.
Publicado: (2020)

SARS and West Nile Virus
por: Loeb, Mark B.
Publicado: (2009)

West Nile Virus in Brazil
por: Costa, Érica Azevedo, et al.
Publicado: (2021)

West Nile Virus Infection
por: Llorente, Francisco
Publicado: (2023)

RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection
por: Stone, Amy E. L., et al.
Publicado: (2019)

Virus and Host Determinants of West Nile Virus Pathogenesis
por: Diamond, Michael S.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_kv4lk5e17bcjltks59uukctkp8