COM-1 Promotes Homologous Recombination during Caenorhabditis elegans Meiosis by Antagonizing Ku-Mediated Non-Homologous End Joining

Successful completion of meiosis requires the induction and faithful repair of DNA double-strand breaks (DSBs). DSBs can be repaired via homologous recombination (HR) or non-homologous end joining (NHEJ), yet only repair via HR can generate the interhomolog crossovers (COs) needed for meiotic chromo...

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Detalles Bibliográficos
Autores principales: Lemmens, Bennie B. L. G., Johnson, Nicholas M., Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567172/
https://www.ncbi.nlm.nih.gov/pubmed/23408909
http://dx.doi.org/10.1371/journal.pgen.1003276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567172/
https://www.ncbi.nlm.nih.gov/pubmed/23408909
http://dx.doi.org/10.1371/journal.pgen.1003276

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