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A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion but Not Egress

Apicomplexans are obligate intracellular parasites that actively penetrate their host cells to create an intracellular niche for replication. Commitment to invasion is thought to be mediated by the rhoptries, specialized apical secretory organelles that inject a protein complex into the host cell to...

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Detalles Bibliográficos
Autores principales: Beck, Josh R., Fung, Connie, Straub, Kurtis W., Coppens, Isabelle, Vashisht, Ajay A., Wohlschlegel, James A., Bradley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567180/
https://www.ncbi.nlm.nih.gov/pubmed/23408890
http://dx.doi.org/10.1371/journal.ppat.1003162